I just got done building a rather mean desktop with a fast chip and a nasty graphics card, running Kubuntu because I like Cinnamon better than Unity.
I keep all my business stuff in a VMware image, because it has to be on Windows, and that way it can’t pollute my lovely pristine Kubuntu machine. :-) Plus, when I travel, I can just move my VMware to my laptop (which also runs Kubuntu) and life is good.
Not that moving 70 GB back and forth is fast, but its no big deal if you plan it out. :-)